Anorexia nervosa essays

Anorexia nervosa papers Anorexia Nervosa is one of the most ordinarily known but then least perceived dietary issues. Anorexia is a psychological sickness, which influences the two young men and young ladies inside typical weight ranges who think they are overweight. The beginning periods of Anorexia are regularly hard to identify. An individual should comprehend what to search similar to early indications and recognize what steps to take to help, yet the most significant thing is attempt to make sense of what hidden issues could be answerable for the condition. Anorexia starts with sentiments of self-assurance and higher confidence as the consequence of an increasingly alluring appearance causing the individual to feel as though they are progressively equipped for taking care of social collaboration (Anorexia, Dying to Be Thin p.1-13). As the anorexia advances, his/her distraction with remaining flimsy, which the person accepts gave his/her sentiments of achievement, caused his/her to focus considerably more on his/her weight (Anorexia, Dying to Be Thin p.1-13). In the end, the anorexic's body will begin to break down, his/her confidence will lessen, and the individual in question will start to expel themselves from social collaboration (Anorexia, Dying to Be Thin p.1-13). Correspondence with his/her family or companions will likewise be diminished or stressed (Anorexia, Dying to Be Thin p.1-13). Before all else stages an individual could see that the anorexic is practicing exorbitantly or inclined to hyperactivity. (Anorexia, Dying to Be Thin p.1-13). The anorexic will show strange eating practices, and continually express the dread of putting on weight, despite the fact that they don't. Anorexics are regularly high achievers. The person will be one of the instructor's top choices, since they never cause any difficulty and think their best is rarely sufficient (Anorexia, Dying to Be Thin p.1-13). Also, they never sass their folks, and never whine (Anorexia, Dying to Be Thin p.1-13). On the off chance that the anorexic falls flat, she fears that individuals won't have anything to do with her. Anorexics se... <! Anorexia Nervosa articles Anorexia Nervosa is an intense ailment that is tormenting numerous youngsters in our general public. This is something that is turning out to be increasingly pervasive. It is something that ought not be trifled with. I have decided to do my Science report on this theme, since it is something charming and it is found in numerous youngsters. This is a point that is excessively unfamiliar to numerous individuals and they should be instructed regarding the matter. I want to help that in any case I can. In the accompanying sections I will talk about the notice indications of anorexia, the individuals influenced by the sickness, the malady itself, and particular kinds of medicines for the confusion. Right off the bat, I might want to talk about the notice indications of a dietary problem. The physical side effects are a lot simpler to distinguish, so I will begin with them. The first and most evident sign is outrageous weight reduction, which you can without much of a stretch recognize. To attempt to hide this the anorexic will begin to wear loose apparel trying to hide the weight reduction. An anorexic will likewise make each endeavor to stay away from a circumstance where food or suppers are served. Occasions such as this will be entirely awkward to them, since it leaves them defenseless against inquiries concerning their dietary patterns. This is something they need to stay away from no matter what. Another piece of dodging suppers is to get ready enormous dinners for gatherings of individuals and eat practically nothing. The anorexic will give pardons like, I'm to tired to eat, or, No, that is alright you should simply eat. I set it up for you. This we should them free as fa r as they could tell. They make it look as they are too drained after all the difficult work they have placed in and as a rule no one causes to notice it. An anorexic may likewise begin to lose hair on their head or start to develop better hair on the body. This is one sign that you will need to search for on the off chance that you have the chance. It will be a precise indication of a dietary issue. Likewise, an individual with a dietary issue will show distinctive sort... <! Anorexia Nervosa papers Numerous past examinations in Anorexia Nervosa have indicated that the explanations behind it are as unpredictable and different as the districts and social orders it happens in, Most examinations have been constrained to the U.S. what's more, Europe or other similarly monetarily flourishing nations. However, in this article I wish to concentrate on Anorexia in such Confucianist social orders as Japan or Korea; which in Asia are the most monetarily fruitful countries state-of-the-art. The greater part of the information gave inside this article is gotten from my own frightening involvement in Anorexia while living in Korea for a range of 18 years, of which the past 8 were commited to my battle with Anorexia. What's more, the involvement in others with similar issues that I experienced while institutionized in clinical offices. I. Family Values Based on Confucianism: The First Born and the Woman In each family in Korea there is a male centric figure, principally the granddad. And afterward There is the beneficiary obvious dad. And afterward there is the main conceived child which is to be prepared to be next inline to protect the family. The principal conceived child is eagerly prepared from numerous points of view. He is prepared to as a matter of first importance regard his folks and grandparents undeniably. There is no space for your own feeling or questions as long as they are alive. There choices are supreme until they state in an unexpected way. This is the most significant factor that a previously conceived child must learn. For instance, there is an old Korean tale about a caring child and his significant other who confronted with starvation choose to sear and serve their lone youngster to their folks (to the spouse the inlaws) in light of the fact that the way they see it you just have one dad or mother yet kids? You just can have more if you pick. This sort of reasoning is engraved in the brain. Second, you are educated to continuously have the option to accomplish the best expectations in everything all that you lock in in, for the most part examines. You must have the option to b... <! Anorexia Nervosa expositions Everyone eats. Nonetheless, as per the human conduct, there are enormous contrasts between individuals. Some eat increasingly, some eat less, some put on weight effectively, and different doesn't. What's more, a few people go to such limits that they hurt themselves, by eating excessively or excessively little. Therefore they may hurt their wellbeing and go to the consideration of specialists. This exploration manages anorexia nervosa. Anorexia nervosa is a dietary problem that generally strikes ladies. Of the 7,000,000 ladies matured 15 to 35 who have a dietary problem, many will bite the dust from the confusions of anorexia. Anorexia may not be seen in the beginning times since it frequently begins as a guiltless eating routine. They regularly become hyperactive on the grounds that they practice quickly trying to consume calories to get more fit. There are numerous reasons with regards to why ladies create anorexia nervosa. One is that it is slimming down taken to a risky extraordinary. Another is that cultural weights direct a lady be slender so as to be excellent - the whithered stray look was as of late mainstream. In any case, what these hypotheses come down to is an issue of control. Whatever else is going on in the anorexic's life, the one thing that she believes she can control is food. Anorexia starts with the regular eating fewer carbs that is so much a piece of young person life. About 33% of anorexia victims have been overweight before beginning to slim down. In contrast to typical eating less junk food, which stops when the ideal weight is reached, in anorexia the eating less junk food and the loss of weight proceed until the victim is well beneath as far as possible for her age and stature. The little measure of calories that she is taking in might be masked by the amounts of organic product, vegetables and plates of mixed greens that she eats. Additionally, she will regularly practice overwhelmingly or take thinning pills to keep her weight low. In addition, notwithstanding her own demeanor to eating, she may take an ardent enthusiasm for purchasing food and preparing for other people. ... <! ANOREXIA NERVOSA expositions Anorexia Nervosa Models are pretty and meager and are regularly taken as good examples of achievement. Anyway they should be underweight to look great on TV and magazines. So as to be slight, they build up an infection called anorexia nervosa. Despite the fact that anorexia and bulimia are identified with dietary problems, anorexia nervosa has more foundation than bulimia. This exposition states what anorexia nervosa is and for to what extent the malady has been around in the public arena. There is increasingly tan one meaning of anorexia nervosa; be that as it may, all portray a similar issue. Here are a portion of the definitions: Anorexia nervosa is an eating issue that happens when an individual is ridiculously worried about being overweight and in this way eat as meager as could be expected under the circumstances. This condition is both a physical sickness and a mental disease. Hormone changes result from the low weight and low degrees of muscle to fat ratio. In young ladies mo nthly cycle stops. Anorexia nervosa can be exceptionally extreme disease, including a danger of death from starvation (Encarta Encyclopedia, Internet). Anorexia nervosa is a confusion wherein distraction with consuming less calories and slenderness prompts over the top weight reduction. The individual may not recognize that weight reduction or limited eating is an issue (www.anorexia.com, Internet). The American Anorexia Nervosa Association characterizes anorexia as a genuine ailment of intentional self-starvation with significant mental and physical parts. Now that we recognize what anorexia implies, lets describe how this infection came to be perceptible. We have the information that anorexia nervosa is influencing a more prominent number of people. In spite of the fact that it was found not very far in the past, anorexia nervosa has been around for a long time. As indicated by Neuman, there is proof of the nearness of an indistinguishable condition that returns from old occasions , well before the finding was characterized. Afterward, in the Middle Ages, goodness was compared with slenderness. The acceptanc

Law of Agency free essay sample

The operator has capacity to influence the principal’s lawful position versus an outsider e. g. by going into an agreement or discarding the property of the head. Office has been characterized in various manners by various researchers. As per Fridman in his book ‘Law of Agency,’ ‘Agency is the relationship that exists between two people when one called the specialist is considered in law to speak to the next considered the head so as to have the option to influence the principal’s legitimate situation in regard of aliens to the relationship by the creation of agreements or the mien of property. Bowstead has characterized office as: ‘The relationship that exists between two people one of whom explicitly or impliedly assents that the other ought to speak to him or follow up for his benefit and the other of whom comparatively agrees to speak to the previous or so to act. We will compose a custom paper test on Law of Agency or on the other hand any comparable subject explicitly for you Don't WasteYour Time Recruit WRITER Just 13.90/page ’ Prof. Powell characterized a specialist as: ‘A individual who is approved to represent a head and who has concurred so to act and who has the ability to influence the legitimate relationship of his vital opposite an outsider. The American rehashing of the law of office characterizes office as: ‘The relationship which results from the indication of assent by one individual to another that the other will follow up for his benefit and subject to his control and assent. ’ For the situation of Ikemefuna C. Amadiume Anor v. Mrs Agnes Solomon Ibok (2006) All FWLR pt 321 pg. 1247, the Court of Appeal characterized an operator as: ‘Any individual who represents another in the limit of appointee, steward, lease authority or some other specialist or trustee on vow. ’ Also, in E. A. Okoyode v. FCDA (20006) All FWLR pt 298 pg 1200 at 1405, the Court of Appeal likewise characterized an operator as ‘One who is approved to represent or instead of another. ’ Here, the Court of Appeal was really citing the Black’s Law Dictionary seventh version. Seavey characterized organization as: ‘A consensual relationship. ’ This Seavey’s definition has gotten legal endorsement in Garnac Grain Company Ltd v. HMF Faure Fair Clough Ltd. (1967) 2 All ER pg 353. All things considered, Lord Pearson stated, ‘The relationship of head and operator must be built up by assent of the head and the specialist. They would be held to have assented on the off chance that they had consented to what sums in law to such a relationship regardless of whether they don't remember it themselves and regardless of whether they have claimed to repudiate it. ’ Note that this announcement has been reprimanded by Fridman. This is on the grounds that this thought of assent as the premise of office relationship is contestable in light of the fact that there are conditions wherein the office relationship exists without the assent of the gatherings or even against the desires of both of them or even them two. See for instance Phibbs v. Boardman (1965) 1 All ER pg 849. All things considered, the litigant who was not named as an operator yet went about as one and made mystery benefits was constrained by the court to return over the mystery benefits to the recipients. This shows a portion of the commitments of a specialist are forced by the law paying little heed to the understanding of the gatherings. There are different examples in which office relationship isn't by assent yet by activity of law. Models are organization of need and an abandoned wife’s option to vow the husband’s credit. Operators DISTINGUISHED FROM PERSONS IN SIMILAR CIRCUMSTANCES Agent and Trustee A specialist and a trustee involve comparable position. Both the operator and the trustee manage the property for and for the benefit of someone else. While an operator manages the principal’s property, a trustee does as such, for the benefit of the recipient. Thus, them two can influence the lawful situation of the individual for whose benefit they are acting. An operator can sell and move the principal’s property to an outsider. A trustee can likewise move the trust property to an outsider. Similarly as a chief can follow, in organization, his property in the hand of a thirdh, party, a recipient can likewise follow his trust property in the hands of an outsider in trust elationships. A trustee is a guardian and an operator is likewise a trustee. The two of them possess a guardian position. In this manner, a specialist must not make mystery benefits similarly as a trustee. An operator and a trustee must not act such that will strife with their obligations. Coming up next are anyway the significant territories of differentia tion between the specialist and the trustee. Though a trustee is the legitimate proprietor of a trust property, an operator is certifiably not a lawful proprietor of the principal’s property. Besides, a specialist can generally speak to the head inside the extent of his property. Then again, a trustee doesn't speak to the recipient similarly as the specialist speaks to the head. Thirdly, organization relationship somewhat depends on assent. A trustee and recipient relationship isn't really founded on assent between the trustee and the settlor. Once more, the relationship of head and operator emerges generally because of the appearance of assent. In this manner, an operator typically makes a legally binding connection between the head and an outsider. Operators, Servants Independent Contractors All these individuals are locked in to follow up for someone else. An ace has a privilege of control on how a hireling should complete his obligations. This privilege doesn't exist on account of a self employed entity or potentially on account of an operator. Note anyway that this control test according to worker, operator and self employed entity has been scrutinized to recognize the situation of a specialist and that of a hireling. The fundamental differentiation between an operator, hireling and self employed entity is one of capacity. An operator is locked in to make contracts and to arrange the property of the head. Really, the obligations can cover in a solitary circumstance. This is on the grounds that a solitary individual can act both as a worker and an operator while being a self employed entity. A solitary individual may play out the obligations of these 3 classifications. Operator AND BAILEE A bailee is an individual who has ownership of merchandise from or for the proprietor of the products for a particular reason. The idea of bailment covers with that of organization particularly where the operator gets ownership as a factor or a trade specialist. Production OF AGENCY Formalities There are no conventions required for the arrangement of an operator and this has been satisfactorily or briefly put by Lord Cranworth in Pole v. Leask ‘No one can turn into the specialist of another with the exception of by the desire of that other individual. His will might be showed recorded as a hard copy or orally basically by putting another in a circumstance which as per customary use of humankind that other is comprehended to speak to and represent the individual who has so positioned him. ’ An arrangement for instance could be sending merchandise to a barker or representative. Limits The general principle is that both the head and the operator must be equipped for going about as head and specialist. This is represented by the general guideline of agreement. In any case, see what Lord Denning said on account of Shepherd v. Cartwright (1953) 2 All ER page 608 especially page 618-619 where he said ‘The arrangement by a newborn child of an operator has consistently been void. ’ Incidentally, a similar Lord Denning withdrew in a later instance of G v. G (1970) 3 All ER pg 546 at 549. It was held that: ‘An baby could name an operator to pay upkeep for the help of his ill-conceived youngster, since that was a legitimate represent him to do and one which he could be constrained to do. Where the chief experiences mental confusion, the general principle is that the agreement is all things considered authoritative on him except if he can demonstrate that he was so crazy as not to recognize what he was doing and this was known to the next gathering. See the instance of Imperial Loan Company v. Stone (1892) 1 QB pg 599. Note anyway that on account of Young v. Toynbee (1910) 1 KB pg 215, the madness of the chief was held to end his agent’s authority consequently, despite the fact that the operator didn't know about the craziness. Commitments OF AN AGENCY RELATIONSHIP Duties of an operator An operator having acknowledged to be a specialist, has certain obligations to perform. Such obligations may emerge from: The understanding he has gone into with the head From the trustee idea of the office relationship By and huge, coming up next are the obligations of a specialist. Execution Where the organization is an authoritative one, an operator must perform what he has attempted to perform under the agreement. This implies the specialist is compelled by a solemn obligation to complete the agreement that he has made to the head. This is represented by the standard of agreement. See Turpin v. Bilton (1843) 5 M G at pg 455. All things considered, a specialist was selected by direct to guarantee the principal’s transport. He neglected to do as such and the boat was lost adrift. It was held that the operator was liable of a break of agreement and accordingly, he was at risk. It must be noted anyway that a specialist will undoubtedly play out an unlawful endeavor or an exchange which is invalid and void either at customary law or under rule. See Cohen v. Kitttel (1889)2 QB d at pg 680. All things considered, a specialist was approached to take a wager for the head. He neglected to do as such. The chief sued him for non-execution. It was held that wagering was unlawful thus the specialist was not subject for break of agreement. Where the organization relationship is non-authoritative, in other words, where it is unwarranted, a specialist isn't obliged to play out the endeavor by any means. It has been contended that in such an example, the operator won't be obligated for non-execution or inability to complete his obligation towards the head. See Ibadan City Council v. Odukale (1972) 8 SC 128. The inquiry

Argumentative Essay Samples - Writing A Thesis Statement

Argumentative Essay Samples - Writing A Thesis StatementA thesis statement is used in some university classes to analyze your research or dissertation. A thesis statement is a summary of your research findings and it can consist of several sections, each with a different focus. Most university classes will use thesis statements as part of their evaluation.The first part of the thesis statement is the introduction section. This section is simply a list of important sections of your work. It is a good idea to include examples of what sections you used in your research. An example can be found in a dissertation or the journal article you wrote.The fourth section should be the conclusion. The conclusion should summarize what you found and conclude with a summary of the study. In most cases, the conclusion section also includes a bibliography section to which you should attach all of your references.The first thing you need to do is write an introduction that contains a summary of what yo u have discovered and an overview of your primary source document. The introduction must be brief and not confuse your reader. You should put a lot of emphasis on the material that you find of relevance to your subject.The next section of the thesis statement should be the body, and this is where you begin to develop your argument. It is usually in this section that you start to formulate an argument. The purpose of the body is to provide information about your research, and this information should be structured as clearly as possible so that your reader will understand what you are trying to say.The last section of the thesis statement is the conclusion and this should contain your summary. The summary should be a summary of the most important points in your argument and should be clear and well organized. It should also contain the bibliography at the end of the summary.When you are writing a thesis statement you should not try to be too formal, but you should also make sure that the statement is brief and to the point. The goal is to capture the reader's attention and then you will have to develop the thesis. If you do not get your thesis written down, you will probably forget it after the discussion portion of the class ends.It is important to spend a few minutes thinking about the things that you are going to write about. Then spend some more time thinking about how you are going to say it. This way you can be sure to include everything that you need to write your thesis statement.

Drugs The Use Of Heroin - 1614 Words

The Use of Heroin My name is Destiny Marcum and I have never been addicted to drugs, but I have seen it first hand through my parents. My parents were heroin addicts for seven years and it made life extremely difficult for them as well as my siblings and me. I am currently in the process of receiving a degree in human services and have a certification in Addiction Studies. I think my parent’s addictions growing up greatly led to my desire to learn about addiction and helping others in this career field. Heroin is an extremely addicting and dangerous man-made recreational drug that has euphoric and even deadly effects for the user. (Anderson, 2014) Heroin is typically injected into the user’s vein but can also be smoked, snorted, orally†¦show more content†¦Although it is made from morphine, it is 2-3 times more potent. As early as 3400 BC, the opium poppy flowers were grown and harvested in Mesopotamia. Now it is grown and harvested in many countries to produce heroin and illegal drugs. Heroin is generally illegal to make, possess, or sell without a license. The term Heroin came into play in 1895, it came from the German word heroisch meaning heroic from the German Bayer medicine corporation. It received this name because of its believed heroic actions by the user. Starting in 1898 and continuing till 1910 Bayer promoted Heroin as being a non-addictive substitute for morphine as well as a cough suppressant. In some countries, Heroin also served medical purposes and was used as a powerful form of pain relief for severe physical trauma, post-surgical pain, and chronic pain caused by end-stage cancers and other terminal illnesses. Heroin is classified as a Schedule I drug under the Controlled Substances Act of 1970 and has no medical use in the United States due to the dangers and risks associated. (Anderson, 2014) Current Uses of Heroin Nearly 80 percent of Americans using heroin reported misusing prescription opioids prior to using the drug. While prescription opioid misuse is a risk factor for starting heroin, only a small fraction of people who misuse pain relievers switch to heroin. Prescription opioid misuse is just one factor leading to current users and heroinShow MoreRelatedHeroin Use And Misuse Of Drugs796 Words   |  4 PagesHeroin use and misuse are certainly nothing new to America, although most people probably could not cite its true origin or history, knowing only what is portrayed on television and movies. Heroin invokes images of dirty needles and equally dirty individuals, barely conscious, and lying in their own filth amongst hollowed, abandoned and dilapidated buildings. These are the images portrayed in movies and promoted among mass media, these are the images conjured when one speaks of heroin addictionRead MoreHeroin Drug Use And Its Effects On The United States951 W ords   |  4 PagesHeroin is an addictive, illegal opioid painkiller derived from morphine. This analgesic drug produces stress-relieving effects along with a sense of euphoria. Addiction to heroin generally begins as an addiction to another substance: marijuana, alcohol, cocaine, or prescription painkillers. Overdose on heroin can cause many complications including coma and death. This risk is commonly increased by combining heroin with alcohol or by cutting it in with other drugs. Injection of heroin also puts oneRead MoreSubstance Misuse Practices : Binge Drinking, Prescription Drug Abuse And Heroin Use Among Young Adults1994 Words   |  8 PagesThe following section discusses key strategies to address the substance misuse practices such as: binge drinking, prescription drug abuse and heroin use among NH young adults. The main sub-themes identified by young adults include: academia education, community resources, outreach education, family and friends, peer involvement, key m essages and alternative strategies. Glad these (focus) groups exist, educating, helping. It s wicked important to feel like my opinion mattersRead MoreHeroin1726 Words   |  7 PagesHeroin Samantha Garza COM/172 02/29/2012 William Pinney Heroin â€Å"She was in a coma. She suffered brain damage and was paralyzed from the neck down; her one-time heroin use left her needing around-the-clock care.† (Bubala 2011, pgs. 1-2). This is an example of what Heroin can do to a young adult who tried the drug for the first time. Although Heroin may be a satisfying new experimental drug to young adults, Heroin is an addictive drug that destroys the human body, and canRead MoreDrug Abuse Has Become A Real Problem1235 Words   |  5 PagesHeroin In the world today, drug abuse has become a real problem. In the 1800s there was a drug called opium that was commonly used. Opium came from the poppy seed plant and became very popular here in America, starting in the west. There used to be opium dens where cowhands would stop and stay and smoke opium. From opium, along came the drug morphine. Morphine was derived from the drug opium and was also introduced in America in the 1800s. Morphine became a very popular pain killer in America duringRead MoreThe Center Of Disease Control And Prevention States, â€Å"From1619 Words   |  7 Pagesstates, â€Å"from 2014 to 2015, heroin overdose death rates increased by 20.6%, with nearly 13,000 people dying in 2015.† Overdosing on opioids has drastically increased over the past few years and has caused many deaths. Throughout the United States, many different cases are reported of individuals who have abused these dangerous opioid drugs. Heroin is known as one of the most common opi oid drugs which leads people to addiction and can consequently lead to overdosing. Using heroin on a daily base or takingRead MoreThe Transformation of Heroin from a Wonder Drug to an Abused Narcotic1082 Words   |  5 PagesThe Transformation of Heroin from a Wonder Drug to an Abused Narcotic In 1898, the Bayer Company in Germany developed an opium derivative ten times more potent than morphine. This new drug was seen as a wonder drug and to suggest the heroic curative power of this new drug, its creators named it heroin. Heroin has transformed over the years from a prominent pharmaceutical drug to a very addictive and misused drug (Freeman 48). Heroin initially was available over the counter and was widelyRead MoreHeroin1347 Words   |  6 Pagesï » ¿Heroin is known as morphine diacetate or diamorphine when it is used in medical environment, it is also referred to as â€Å"black tar† among other names in colloquial language. Alder Wright was the first person to synthesize heroin in 1874 when he added two groups of acetyl to morphine molecules (Rubin, 2013). Heroine is an active drug which can also be used in medicine to treat severe pain that results from heart attack or injuries; it is absorbed in the body as morphine. According to Levert (2005)Read MoreHeroin Addiction And Our Adolescent Patients1661 Words   |  7 Pages Today, we know that Heroin is illegal to use in life, as cocaine and Marijuana; because it is also addicted substance and very effect to physical and brain. Heroin processes from morphine, a natural substance extracts from the seed pod of poppy Plants. It usually sells as a white powder or br own powder and pure heroin is a white powder with a bitter taste, heroin emits in South America, then it appears in U.S and involve at Southeast Asia. There are three ways to use heroin that User can be snortedRead MoreEssay on Heroin1631 Words   |  7 PagesHeroin Heroin, a powerful narcotic, acts upon the brain as a painkiller, increasing physical addiction and ongoing emotional dependence (Schaffer Library of#8230;). Heroin has many challenging and highly risky effects on the user, all the more hazardous if overdosing is present. This extremely dangerous drug, heroin, will never cease being used, but may cease the existence of an individual. Heroin is a painkilling drug that is made from the Papaverum Somniferum, also known as the opium

My Experience At Cedar Hill Collegiate High School

Over the course of my life, I have incurred numerous challenging situations. Although most challenges are short term in in the grand scheme of things, my longest and ongoing challenge would definitely be attending Cedar Hill Collegiate High School. Towards the end of the eighth grade, I had several decisions to make about my future. My mother did not want me to stay at the charter school I was attending, and the majority of my friends had already stated that they were planning to move on. I had very few options at my disposal. I could either attend the regular high school, transfer to Cedar Hill Collegiate High School, or try to convince my mom to let me stay at my current school. The problem with attending Collegiate was that most students believed that it was literally impossible to be accepted, let alone succeed there. It was a school for people deemed to be super nerds. It was a school that was so difficult that it would set you up for failure. Although the thoughts lingered in my head, I knew that of my options, Collegiate was most likely the best one in terms of setting myself up for a bright future. However, when my classmates found out where I was transferring to, some of them scoffed and ridiculed me. They believed that I would not be there for long, or would sacrifice my entire high school career to succeed. They were not shy about stating their opinions, and frequently presented their discouraging speech to me. Though I, too, had heard the horrifying rumorsShow MoreRelatedNursing Essay41677 Words   |  167 PagesE. Shalala (Chair), President, University of Miami Linda Burnes Bolton (Vice Chair), Vice President and Chief Nursing Officer, Cedars-Sinai Health System and Research Institute, Los Angeles, CA Michael R. Bleich, Dean and Dr. Carol A. Lindeman Distinguished Professor, Vice Provost for Interprofessional Education and Development Oregon Health and Science University School of Nursing, Portland Troyen A. Brennan, Executive Vice President, Chief Medical Officer, CVS Caremark, Woonsocket, RI Robert ERead More_x000C_Introduction to Statistics and Data Analysis355457 Wor ds   |  1422 PagesIntroduction to Statistics and Data Analysis This page intentionally left blank Introduction to Statistics and Data Analysis Third Edition Roxy Peck California Polytechnic State University, San Luis Obispo Chris Olsen George Washington High School, Cedar Rapids, IA Jay Devore California Polytechnic State University, San Luis Obispo Australia †¢ Brazil †¢ Canada †¢ Mexico †¢ Singapore †¢ Spain †¢ United Kingdom †¢ United States Introduction to Statistics and Data Analysis, Third Edition Roxy

Don Quixote de la Mancha Essay - 5548 Words

Two lost tales concerning the valiant knight Don Quixote de la Mancha and other such interesting things Prologue After reading for the first time the true history of The Ingenious Hidalgo Don Quixote de la Mancha, originally scribed by the brilliant Arab historian Cide Hamete Benengeli, I was captivated by it and somehow began to relate it to all that happened to me in my daily life, wondering how our famous hero would interpret these things in my life and what I might learn from his good sense if he were here to dictate to me. Don Quixote did not only haunt my mind because I found its contents interesting, but also because I was expected to produce literature of my own about the text and what it said; and so like any writer with a†¦show more content†¦Sitting at a table I imagined my final piece being read by the professor whose opinion of it would count the most, and I imagined him at first being amazed at my writing, but then I remembered that my writing would not be capable of amazing anyone because time is never plentiful enough, so I imagined him just being pleased with my work ; and it is at this thought that I got up to look around at the shelved books nearby to my seat and started thumbing through them to see what I could see—because it is the way of men with too little time to look for inspiration wherever it can be found to somehow slow down time or, better yet, speed up their productivity. The genre of those books entirely consisted of the type that one refers to when he or she is lacking the skills to create a delicious meal on his or her own, the kind of book the library I was in is claimed to contain more of than any other library. There was one book, though, that stood out from the rest, so I took it from the shelf and turned it over in my hands to find the title, but there was no title, and in fact there was no writing in the first few pages to pronounce the title or author of it. It was not until I got to the sixth or eighth page that I found any writing, and it said: The Two Lost Tales About the Valiant Knight Don Quixote de la Manc ha. One cannot express theShow MoreRelatedDon Quixote de La Mancha1223 Words   |  5 PagesIn Miguel de Cervantes classic novel Don Quixote de la Mancha, a necessary counterpart to Don Quixotes character is found in Sancho Panza. Sancho is Don Quixotes so-called squire and companion through his adventures. The vital contrast between these two characters contributes to the literary success of Cervantes novel. It is only through the eyes of Sancho that we witness Don Quixotes madness and only through the latters madness that we evidence Sanchos sanity. Without the presence of theseRead MoreDon Quixote De La Mancha1770 Words   |  8 Pages Don Quixote De La Mancha In the world of literature, there are many great world that blow the minds of readers and historians everywhere. However none of these works of literature have caused a great effect in the world quite like Don Quixote De La Mancha, a novel written by Miguel de Cervantes in the 1600s. Don Quixote de la Mancha is the jewel of Western Literature. It is the most commonly translated and read book in the universe of Spanish literature, after the bible. 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Consciousness free essay sample

Consciousness, as the book stated, really can be a funny thing. As I delved into Chapter 3, my consciousness immediately began to drift away. I was telling myself in my head how â€Å"I have to try to read as much of this chapter tonight, so I could focus on the writing the next day†. Funny thing is I didn’t actually notice what was happening until I read â€Å"And then there are those times when consciousness seems to split. Reading Green Eggs and Ham to my preschooler for the umpteenth time, my obliging mouth could say the words while my mind wandered elsewhere. † However, I also had to reread a chunk of the text because even though my eyes were reading, my mind didn’t quite grasp any of what I’d just read while I was pondering about the reading and writing assignment. At first, I couldn’t quite comprehend what the book was talking about when it mentioned The Two-Track Mind or spoke of Dual Processing. We will write a custom essay sample on Consciousness or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page But suddenly I saw it from a different perspective and it just clicked. Computers have different kinds of processors; dual-core processors boost the system’s multitasking computing powers. So the same must be true for dual processing, allowing us to do more things at once. However, dual-core processing computers are able to efficiently handle intensive tasks, where we are limited; according to this passage on The Two-Track Mind â€Å"Serial conscious processing, though slower than parallel processing, is skilled at solving new problems, which require our focused attention†¦ Tap a steady beat three times with your left hand while tapping four times with your right hand. Both tasks require attention, which can be in only one place at a time. † This is true, for I have noticed that I’m unable to perform at my usual skill level on video games when trying to hold  a conversation. The conversation, just as much as the video game requires my attention, so I must sacrifice my attention on one in order to do the other. Likewise, the reason I wasn’t able to comprehend what I read earlier, while my consciousness drifted, was because of something called Selective Attention. I’ve always been disturbed with the fact that most of us will spend a third of our entire lives sleeping. I’d always thought of sleep as a waste of time, but something that the body needed in order to function properly. But now I’m intrigued with the mystery that lies in that 3rd of our lives. â€Å"Thirty-seven percent of people report rarely or never having dreams that they can remember the next morning†(Moore, 2004). Unknown to those people, they spend about 600 hours a year experiencing some 1500 dreams, or more than 100,000 dreams over a typical lifetime—dreams swallowed by the night but never acted out, thanks to REM’s protective paralysis. â€Å"While sleeping, you may feel dead to the world, but you are not. Even when you are deeply asleep, your perceptual window is not completely shut. † This is very true, I’ve noticed there are certain things, mainly sounds, that even when asleep, I tend to respond to. Such as hearing my name, as the book states, but even sounds like the meow of my cat. But, it’s also mentioned how â€Å"The occasional roar of passing vehicles may leave your deep sleep undisturbed. † Which makes me wonder why some sounds and not others, is it dependent on something simple such as the volume or pitch of the sound, or perhaps something more complicated and deeper such as how they are related to us, past experiences, or their importance in our lives?

Harry Potter And Sorcerer Stone By Rollings Essays - Draco Malfoy

Harry Potter And Sorcerer Stone By Rollings In the book, Harry Potter and The Sorcerer`s Stone, Written by J.K. Rollings, I believe that courage is the most outstanding theme. J.K. Rollings does a wonderful job of expressing it in this book. Al though there are many other themes I feel that courage is by far the most important. Harry shows courage when he tries to catch Neville?s ?rememberall? that Malfoy threw, from crashing to the ground. Harry had to have courage to get on the broom for the first tome without anyone helping him. He had to have even more courage to stand up to Malfoy for throwing Neville?s the ?rememberall? and trying to break it. Harry also needed courage to sneak out and try to find out who Flamel was and/or is. He could have gotten detention or even expelled for sneaking out but Harry thought that it was very important and worth the risk for him to sneak out of his room after curfew. Harry showed the most courage when he tries to stop Quirell from stealing the sorcerer?s stone. He knew that by doing this he was risking detention, expulsion, and even death, but the fate of the world depended on his doing this. He had many chances to turn back but took none of them. He wouldn?t even think about it. He knew that many lives depended on his saving the stone. Even though he knew he would have to fight the thing that killed his parents and tried to kill him he pressed forward until the final battle. Out of all the themes that were shown in this book I still believe that courage is the most important and outstanding one. Harry Potter and the Sorcerer Stone is a wonderful book with many great themes. It is first of a series of seven, three of which have already been released.

The Greatest Ninja Battle in 1581

The Greatest Ninja Battle in 1581 It was a lawless era in Japan, with petty feudal lords fighting a never-ending series of small wars over land and power. In the chaotic Sengoku period (1467-1598), the peasants often ended up as cannon-fodder or incidental victims of the samurai wars; some commoners, however, organized themselves to defend their own homes, and to take advantage of the constant warfare. We call them the yamabushi or ninja. The key ninja strongholds were the mountainous provinces of Iga and Koga, located in what are now Mie and Shiga Prefectures, respectively, in southern Honshu. Residents of these two provinces gathered information and practiced their own techniques of espionage, medicine, warfare, and assassination. Politically and socially, the ninja provinces were independent, self-governing, and democratic - they were ruled by town council, rather than by a central authority or daimyo. To the autocratic nobles of other regions, this form of government was anathema. Warlord Oda Nobunaga (1534 - 82) remarked, They make no distinction between high and low, rich and poor... Such behavior is a mystery to me, for they go so far as to make light of rank, and have no respect for high ranking officials. He would soon bring these ninja lands to heel. Nobunaga embarked on a campaign to reunify central Japan under his authority. Although he did not live to see it, his efforts began the process that would end the Sengoku, and usher in 250 years of peace under the Tokugawa Shogunate. Nobunaga sent his son, Oda Nobuo, to take over the province of Ise in 1576. The former daimyos family, the Kitabatakes, rose up, but Nobuas army crushed them. The surviving Kitabatake family members sought refuge in Iga with one of the Oda clans major foes, the Mori clan. Oda Nobuo Humiliated Nobuo decided to deal with the Mori/Kitabatake threat by seizing Iga Province. He first took Maruyama Castle early in 1579 and began to fortify it; however, the Iga officials knew exactly what he was doing, because many of their ninja had taken construction jobs at the castle. Armed with this intelligence, the Iga commanders attacked Maruyama one night and burned it to the ground. Humiliated and furious, Oda Nobuo decided to attack Iga immediately in an all-out assault. His ten to twelve thousand warriors launched a three-pronged attack over the major mountain passes in eastern Iga in September 1579. They converged on Iseji village, where the 4,000 to 5,000 Iga warriors lay in wait. As soon as Nobuos forces had entered the valley, Iga fighters attacked from the front, while other forces cut off the passes to block the Oda armys retreat. From the cover, the Iga ninja shot Nobuos warriors with firearms and bows, then closed to finish them off with swords and spears. Fog and rain descended, leaving the Oda samurai bewildered. Nobuos army disintegrated - some killed by friendly fire, some committing seppuku, and thousands falling to the Iga forces. As historian Stephen Turnbull points out, this was one of the most dramatic triumphs of unconventional warfare over traditional samurai tactics in the whole of Japanese history. Oda Nobuo escaped the slaughter but was roundly chastised by his father for the fiasco. Nobunaga noted that his son has failed to hire any ninja of his own to spy out the enemys position and strength. Get shinobi (ninja)... This one action alone will gain you a victory. Revenge of the Oda Clan On October 1, 1581, Oda Nobunaga led about 40,000 warriors in an attack on Iga province, which was defended by approximately 4,000 ninja and other Iga warriors. Nobunagas massive army attacked from the west, east, and north, in five separate columns. In what must have been a bitter pill for Iga to swallow, many of the Koga ninja came into the battle on Nobunagas side. Nobunaga had taken his own advice about recruiting ninja assistance. The Iga ninja army held a hill-top fort, surrounded by earthworks, and they defended it desperately. Faced with overwhelming numbers, however, the ninja surrendered their fort. Nobunagas troops unleashed a massacre on the residents of Iga, although some hundreds escaped. The ninja stronghold of Iga was crushed. Aftermath of the Iga Revolt In the aftermath, the Oda clan and later scholars called this series of encounters the Iga Revolt or the Iga No Run. Although the surviving ninja from Iga scattered across Japan, taking their knowledge and techniques with them, the defeat at Iga signaled the end of ninja independence. A number of the survivors made their way to the domain of Tokugawa Ieyasu, a rival of Nobunagas, who welcomed them. Little did they know that Ieyasu and his descendants would stamp out all opposition, and usher in a centuries-long era of peace that would make ninja skills obsolete. The Koga ninja did play a role in several later battles, including the Battle of Sekigahara in 1600, and the Siege of Osaka in 1614. The last known action that employed Koga ninja was the Shimabara Rebellion of 1637-38, in which ninja spies aided the shogun Tokugawa Iemitsu in putting down Christian rebels. However, the age of the democratic and independent ninja provinces ended in 1581, when Nobunaga put down the Iga Revolt. Sources Man, John. Ninja: 1,000 Years of the Shadow Warrior, New York: HarperCollins, 2013. Turnbull, Stephen. Ninja, AD 1460-1650, Oxford: Osprey Publishing, 2003. Turnbull, Stephen. Warriors of Medieval Japan, Oxford: Osprey Publishing, 2011.

THE THEORIES BEHIND MANAGEMENT Essay Example | Topics and Well Written Essays - 2500 words

THE THEORIES BEHIND MANAGEMENT - Essay Example It should be unequivocally stressed that managers who have applied management theory in there daily operations have high chances of accomplishing both personal and organizational objective. To address this subject, the study paper will carry on along the following field: management will have to be defined for reasons of theoretical clarity; management functions, objectives, goals, and essentials will be underscored; reasons to study management theory will be named; and the various management theories, the centre of the paper, will be discussed at length; and lastly "the way forward" in terms of a conclusion will be provided Management is defined as the art or science, of attaining objectives through individuals. Because managers also oversee, management can be understood to mean literally as "looking over" - i.e. ensuring individuals do what they ought to do. Therefore Managers are, supposed to ensure better productivity or, "continuous improvement". More generally, management is a process of formulating and maintaining an atmosphere in which people, working collectively in groups, ably accomplish selected objectives (Koontz and Weihrich 1990,). In its expanded outline, this fundamental definition means quite a few things. One, as managers, they perform the managerial roles of planning, organizing, leading, controlling and staffing. Two, management pertains to any type of organization. Lastly, the objective of every manager is similar - creating surplus. Basically, then, management involves the acquirement of managerial competency, and efficiency in the following essential areas: problem solving, human resource management, administration, and organizational leadership. Most important of all management is entails solving problem or issues which go on emerging every time in the as an organization struggles to realize its goals, aims and objectives. Problem solving ought to be accompanied with problem identification, assessment and implementation of solutions to managerial problems. (Stoner J. A. et al, 2003) Management Objectives; Functions; Goals; and Essentiality Management Objectives There are principally three management objectives. Ensuring organizational targets and goals are met; secondly looking after health, safety and welfare of staff. Thirdly protecting the apparatus and the resources of the organization, with includes the human resources. (Stoner J. A. et al, 2003) Management Functions To appreciate management, it is very important that we divide it into five managerial functions that are; planning, leading, organizing, controlling and staffing. Planning entails selecting objectives and missions and the actions to realize them. Leading is to influence people so that they contribute to organization and also group goals; it has deals mainly with the interpersonal side of managing. Organizing is that part of management which involves creating an intended structure of roles for individuals to fill up in an organization. Controlling, for instance, budget for expenditure, is the measuring and also correcting of subordinates activities to make sure that events conform to plans. It assesses performance against objectives and plans, illustrates where negative differences exist, and, by putting in motion actions to correct deviations, helps ensure accomplishment of plans. Staffing

Reflective journal Essay Example | Topics and Well Written Essays - 250 words - 3

Reflective journal - Essay Example In addition, I also learnt about colostomies. The high point of my day was doing an IVPB successfully with minimal direction from my clinical instructor. The low point was seeing the patient so nauseas and unable to eat anything and there was nothing I could do to help. The patients on the medical surgery floor received great care. However, the unit should be added two more nurses to ease the amount of workload that they have to do. The nurses in the unit should also be trained on how to handle patients with unique medical conditions. Although I did not encounter any challenge, I know that I can always ask for help from any of the nurses on the medical surgery floor. My interaction with patients presents an opportunity to acquire valuable life lessons. Seeing the patient deal with so much pain with a lot of calm taught me the importance of having courage when I am faced with unpleasant conditions. Lastly, my last day on the medical surgery floor provided a great opportunity to acquire practical nursing skills. I am grateful for all the things that I have learned from the other nurses and the patients. In addition, I have been able to identify my strengths and weaknesses. This experience has not only helped me to grow as a nursing profession but also as a

Growth Factors in Periodontal Regeneration

Growth Factors in Periodontal Regeneration GROWTH FACTORS IN PERIODONTAL REGENERATION ABSTRACT : Periodontitis and all periodontal diseases are bacterial infections that destroy the attachment fibers and supporting bone. Left untreated, these diseases can lead to tooth loss. The main cause of periodontal disease is a bacterial plaque, many options are available to treat this disease including non-surgical,surgical,and recent regenerative materials. GFs are natural biological mediators that regulate key cellular events that are part of the process of tissue repair and regeneration. Recent advances in the areas of cellular and molecular biology allowed better understanding of the functions of GFs and their participation in the different phases of wound healing. In vitro and in vivo studies have confirmed that GFs can enhance the capacity of tissues to regenerate by regulating cell chemo attraction, differentiation and proliferation. This review focuses on five growth factor families that have potential for inducing periodontal regeneration based on their ability to stimulate osteo blast and periodontal ligament cells in vivo and vitro. Key words: platelet-derived growth factor, insulin-like growth factor, transforming growth factor-beta, fibroblast growth factor, and bone morphogenetic protein. INTRODUCTION : Periodontitis is a widely prevalent inflammatory disease of the tissues supporting the teeth, characterized by a progressive loss of bone and attachment. The ultimate goal of periodontal therapy is the regeneration of periodontal tissues, which consists in stimulating new cementum formation, new alveolar bone apposition, and a functionally-oriented periodontal ligament reconstruction. Conventional treatment procedures may be ineffective in achieving bone regeneration, leaving both the clinician and the patient dissatisfied with the outcome. Growth factors (GFs) have long been believed to have the potential to accelerate the healing process and, therefore, enhance tissue regeneration in challenging clinical scenarios.1 MODE OF ACTION OF GROWTH FACTORS: To evoke a biologic effect, a growth factor must be synthesized by an originating cell, travel to its target receptor, interact with target receptor, or binding protein, and activate second messengers or terminal effectors.2,3 Local mode of action is more associated with the term growth factor and involves Paracrine, Autocrine, Juxtacrine, and Intracrine modes. Autocrine mode of action – Growth factors synthesized by one cell, secreted in a soluble form outside the cell and then bind to surface receptors on the same cell to evoke an effect is autocrine mode of action. Example includes: TGF ÃŽ ², which are produced and act on epithelial cells, and BMP’s, which are produced and act on osteoblastic cells. (fig 1) Intracrine mode of action–Growth factors produced by one cell and not secreted, but acts intracellularly to facilitate its effects is intracrine mode of action. (fig 2) Paracrine mode Growth factorsproduced by one cell, with receptors present on another cell in the local micro environment is the paracrine mode of action. Here the mediators are secreted in soluble form and binds to its receptors on the target cell to evoke its effect. (fig 3) Juxtacrine mode It is similar to paracrine effects except that the factor produced by the cell of origin is cell surface bound and requires cell contact by the target cell to evoke a response. (fig 4) RECEPTORS FOR GROWTH FACTORS:4,5 For a growth factor to exert an effect, its designated receptor must be present in sufficient quantity, orientation, and functional activity to transmit appropriate stimuli. Growth factor receptors can be divided into 2 broad categories: Cell surface receptors Intracellular receptors The most common prototype growth factor receptor is the cell surface receptor, which can be further divided into three main categories: G- protein linked Receptor tyrosine kinases Serine threonine receptor kinases POTENTIAL ROLES OF GROWTH FACTORS IN PERIODONTAL REGENERATION: To stimulate cell proliferation. E.g. Platelet derived growth factor (PDGF). To enhance function of cells and cell differentiation. E.g. Bone morphogenetic protein (BMP). To stimulate matrix synthesis. E.g. Transforming growth factor- ÃŽ ² (TGF- ÃŽ ²). To act as co-factors for gene expression. DISADVANTAGES OF GROWTH FACTORS: They were intended to be made by cells, stored than used locally. They have short half-lives i.e., when used as drug, doses must be greater than actual in vivo concentrations. They affect various cells in individual ways i.e., cells growing in high concentrations of growth factor had an increased susceptibility to cell death upon growth factor withdrawal. They need a delivery system for sustained or, controlled release (in low concentration) of a biologically active growth factor or, cocktail of growth factors. POLYPEPTIDE GROWTH FACTORS : Polypeptide growth factors are a diverse group of hormone-like agents that regulate growth and differentiation through cell surface receptors. They are generally represented by homologous families containing several members with distinct overlapping receptor interactions and hence, responsive tissue specificities. Similarly, their receptors are also clustered in family groups of sequence-related proteins. COMMON FEATURES OF POLYPEPTIDE GROWTH FACTORS :6 Natural cell products: Growth factors are natural cell products that are released or activated when cell division is needed.This action typically occurs during such events as wound healing or, tissue regeneration. Local actions: With few exceptions,growth factors are locally acting. Receptor activity: Because growth factors cannot diffuse across the cell membrane, growth factors must exert their activity by first binding to high-affinity cell membrane receptors.The capacity of a cell to respond to a given factor is therefore dependent on the presence of these receptors. Regulation: The production of polypeptide growth factors is tightly regulated in normal cells. In contrast, unregulated production of growth factor is thought to be an important component of proliferative disorders, such as fibrotic disease and cancers. Multifunctional activities: Polypeptide growth factors are multifunctional, meaning that they may stimulate a wide variety of cellular activities, which include growth, migration, differentiation and production of extracellular matrix proteins. Mechanism of action: In some cases, growth factors can stimulate the same cell that synthesizes the molecule (autocrine stimulation) or can affect nearby cells (paracrine stimulation). Regeneration: Tissue regeneration in vivo probably reflects the combined effect of several different growth factors. GROWTH FACTOR APPLICATIONS FOR ORAL AND PERIODONTAL TISSUE ENGINEERING : Therapeutic application of growth factors to restore damaged tissues aims at regeneration through biomimetic processes, or mimicking the processes that occur during embryonic and post-natal development.7 The complexity of these events suggests that creating an optimal regenerative environment requires the combination of different growth factors as found in natural reparative processes. The use of a single recombinant growth factor may also induce several molecular, biochemical and morphological cascades that will result in tissue regeneration.8 The most studied growth factors for periodontal regeneration have been PDGF, IGF, FGF-2, TGF-ÃŽ ² and different BMPs. SI. NO GROWTH FACTOR ALTERNATIVE NAMES SOURCE 1 Platelet-derived growth factor Fibroblast-derived growth factor. Glioma-derived growth factor Degranulating platelets Endothelial cells Smooth muscles Macrophages- Fibroblasts 2 Insulin-like growth factor Erythropoetic factor Growth-promoting activity for vascular endothelial cells Macrophages- Osteoblasts- Plasma stored in bone 3 Transforming growth factor-ÃŽ ² Epithelial cell specific growth inhibitor Tumour-inducing factor-1 Platelet ÃŽ ± granules 4 Fibroblast growth factor family Heparin binding growth factor Macrophage and osteoblasts stored in bone. PLATELET DERIEVED GROWTH FACTOR: The PDGFs are a family of dimeric disulfide – bound growth factors that exert their biologic effects by activating 2 structurally related tyrosine kinase receptors, the PDGF- ÃŽ ± and PDGF – ÃŽ ² receptors. PDGF was the first growth factor to be evaluated in preclinical periodontal and peri-implant regenerative studies. Proliferation, migration and matrix synthesis were observed on cultures of periodontal cells stimulated by PDGF, including gingival and PDL fibroblasts, cementoblasts, preosteo-blasts and osteoblastic cells [9-14]. These effects were shown to be time- and dose dependent 14. The PDGF family is composed of four growth factors: PDGF- A, -B, and the most recently discovered PDGF-C and -D 15. All of these participate in the wound-healing process, but, until now, only the three isoforms PDGF-AA, BB and AB were evaluated in periodontal therapy. PDGF-BB is the most effective on PDL cell mitogenesis and matrix biosynthesis 16,17. INSULIN LIKE GROWTH FACTOR: These are a family of single chain serum proteins that share 49% homology in sequence with pro- insulin. IGF-1 and IGF- 2 are two polypeptides from this group. IGF-1 acts as progression factor, also stimulates bone formation and have an effect on periodontal ligament cells. IGF-I is also important for bone remodeling and maintenance of skeletal mass and plays significant role in age-related osteoporosis. IGF-1 is capable of preventing apoptosis in fibroblasts by activation of multiple signal transduction pathways. IGF-1 has also been shown to regulate DNA and protein synthesis in periodontal ligament fibroblasts in vitro and to enhance soft tissue wound healing in vivo. Furthermore, studies have suggested variable responses of periodontal tissues to IGF-1 depending upon anatomical sites and a differential involvement of IGF-1 in periodontal wound healing and regeneration.18 FIBROBLAST GROWTH FACTOR: The angiogenic and fibroblast stimulatory properties of FGF-2 during wound healing and its chemotactic and proliferative effects on PDL cells suggest its use for periodontal regenerative therapeutic approaches19,20. In preclinical studies, this growth factor was evaluated for the treatment of different types of periodontal bone defects, in dogs and non-human primates. Despite different concentrations of FGF-2 and different delivery systems used in the studies, all showed an improvement in the periodontal tissue regeneration, compared with control groups. Studies that evaluated more than one concentration of FGF-2 suggested that its effects are dose dependent.21,22 TRANSFORMING GROWTH FACTOR ÃŽ ²: It is a member of a large family of biologically active protein hormones that are structurally related but differ markedly in their function. TGF ÃŽ ² consists of 2 subunits held together by covalent bonds. Five different genes are identified that encodes TGF- ÃŽ ² polypeptide TGF-ÃŽ ² has 5 closely related isoforms in vertebrates, out of which 3 are found in mammals (TGF-ÃŽ ²1, TGF-ÃŽ ²2, TGF-ÃŽ ²3). The three major activities of TGF-ßinclude inhibition of cell proliferation, enhancement of extracellular matrix deposition and the exhibition of complex immune regulatory properties. It is a major regulator of cell replication and differentiation. It can stimulate or inhibit cell growth. It can also modulate other growth factors like PDGF, EGF and FGF. It inhibits epithelial cell proliferation and stimulates mesenchymal cells. TGF-ÃŽ ²1, the most abundant isoform of the TGF-ÃŽ ² family and found primarily in the platelets and osseous tissue, has been used for this application.It has a role in recruiting and stimulating osteoprogenitor cells to proliferate and suggests to support periodontal wound healing and regeneration.23 BONE MORPHOGENETIC PROTEINS: The name Bone Morphogenetic Protein was given in 1965 by Urist .Bone morphogenetic proteins (BMPs) are a group of regulatory glycoproteins that are members of the transforming growth factor-beta superfamily.24They stimulate angiogenesis and migration, proliferation and differentiation of mesenchymal stem cells into cartilage and bone forming cells. More than 20 BMP-related proteins have been identified, several of which induce bone formation.25 In the field of periodontal regeneration, much of the research interest has focused on BMP-2, BMP-3 (osteogenin), and BMP-7. Recent studies have utilized recombinant human BMP to determine their potential for correcting intrabony, supra-alveolar, furcation, and fenestration defects. BMPs also show much promise in promoting dental implant wound healing.24 GROWTH FACTOR DELIVERY SYSTEMS: Several matrices and delivery systems have been used and evaluated for their efficacy and biocompatibility as carrier for growth factors. Two common types of polymeric materials used in growth factor delivery strategies are natural collagen-derived materials and synthetic polymers of lactic and glycolic acid (i.e., Poly [lactide-co-glycolide]). Extracellular matrix-derived macromolecules such as collagen have been used for many years in biomaterial application, and it is now possible to create artificial analogues of extracellular matrix proteins using recombinant DNA technology.1 Carriers can be of different types such as solids, gels or combinations.25A variety of new injectable materials such as hydrogels are also being developed for growth factor delivery applications and have been of special interest. These injectables are especially attractive because, in clinical application, they can allow for minimally invasive delivery of inductive molecules.1 CONCLUSION: Growth factors may regulate the repair and/or regenerative process which are impaired in presence of bacteria and their products in periodontal disease. Thus, the objective of growth factors administration in the treatment of periodontitis is to mimic the normal developmental process enhance normal wound healing response to promote complete regeneration of all attachment structures. Basic and clinical research is in progress to evaluate the role of growth factors in periodontal wound healing. BIBLIOGRAPHY: DARNELL KAIGLER, GUSTAVO AVILA, LESLIE WISNER-LYNCH, MARC L. NEVINS, MYRON NEVINS, GIULIO RASPERINI. Platelet-Derived Growth Factor Applications in Periodontal and Peri-Implant Bone Regeneration .Expert OpinBiolTher. 2011 March ; 11(3): 375–385 RIPAMONTI U, HERBST NN, RAMOSHEBI LN. Bone morphogenetic proteins in craniofacial and periodontal tissue engineering: experimental studies in the non-human primate Papioursinus. Cytokine Growth Factor Rev 2005;16(3):357–368. ANUSAKSATHIEN O, GIANNOBILE WV. Growth factor delivery to re-engineer periodontal tissues. Curr. Pharm. Biotechnol 2002;3(2):129–139. FRECHETTE JP, MARTINEAU I, GAGNON G.Platelet-rich plasmas: growth factor content and roles in wound healing. J Dent Res 2005; 84(5): 434-439. LAURIE K. MC CAULEY MARTHA J. Somerman. Biologic modifiers in periodontal regeneration. Dent Clin N Am , Advances in Periodontics, part I 1998; 43(2): 361-387. GARRY R. GROTENDORST. Connective tissue growth factor : A mediator of TGF- ÃŽ ² action on fibroblasts. Mini Review. Cytokine and growth factor reviews 1997, 8(3); 171 – 179. SCHILEPHAKE H. Bone growth factors in maxillofacial skeletal reconstruction. Int. J. Oral Maxillofac. Surg 2002;31(5):469–484. RIPAMONTI U, HERBST NN, RAMOSHEBI LN. Bone morphogenetic proteins in craniofacial and periodontal tissue engineering: experimental studies in the non-human primate Papioursinus. Cytokine Growth Factor Rev 2005;16(3):357–368. NISHIMURA F, TERRANOVA VP. Comparative study of the chemotactic responses of periodontal ligament cells and gingival fibroblasts to polypeptide growth factors. J. Dent. Res 1996;75(4):986–992. SAYGIN NE, TOKIYASU Y, GIANNOBILE WV, SOMERMAN MJ. Growth factors regulate expression of mineral associated genes in cementoblasts. J. Periodontol 2000;71(10):1591–1600. STRAYHORN CL, GARRETT JS, DUNN RL, BENEDICT JJ, SOMERMAN MJ. Growth factors regulate expression of osteoblast-associated genes. J. Periodontol 1999;70(11):1345–1354. CANALIS E. Effect of platelet-derived growth factor on DNA and protein synthesis in cultured rat calvaria. Metabolism 1981;30(10):970–975. BARTOLD PM, RABEN A. Growth factor modulation of fibroblasts in simulated wound healing. J.Periodontal Res 1996;31(3):205–216. OJIMA Y, MIZUNO M, KUBOKI Y, KOMORI T. In vitro effect of platelet-derived growth factor-BB on collagen synthesis and proliferation of human periodontal ligament cells. Oral Dis 2003;9(3): 144–151. REIGSTAD LJ, VARHAUG JE, LILLEHAUG JR. Structural and functional specificities of PDGFC and PDGF-D, the novel members of the platelet-derived growth factors family. FEBS J 2005;272 (22):5723–5741. BOYAN LA, BHARGAVA G, NISHIMURA F, et al. Mitogenic and chemotactic responses of human periodontal ligament cells to the different isoforms of platelet-derived growth factor. J. Dent. Res 1994;73(10):1593–1600. MATSUDA N, LIN WL, KUMAR NM, CHO MI, GENCO RJ. Mitogenic, chemotactic, and synthetic responses of rat periodontal ligament fibroblastic cells to polypeptide growth factors in vitro. J.Periodontol 1992;63(6):515–525. XIAOZHE HAN AND SALOMON AMAR. Role of Insulin-Like Growth Factor-1 Signaling in Dental Fibroblast Apoptosis. J Periodontol 2003;74:1176-1182. TAKAYAMA S, MURAKAMI S, MIKI Y, et al. Effects of basic fibroblast growth factor on human periodontal ligament cells. J. Periodontal Res 1997;32(8):667–675. TERRANOVA VP, ODZIEMIEC C, TWEDEN KS, SPADONE DP. Repopulation of dentin surfaces by periodontal ligament cells and endothelial cells. Effect of basic fibroblast growth factor. J. Periodontol 1989;60(6):293–301. ROSSA C JR. MARCANTONIO E Jr, CIRELLI JA, et al. Regeneration of class III furcation defects with basic fibroblast growth factor (b-FGF) associated with GTR. A descriptive and histometric study in dogs. J. Periodontol 2000;71(5):775–784. TAKAYAMA S, MURAKAMI S, SHIMABUKURO Y, KITAMURA M, OKADA H. Periodontal regeneration by FGF-2 (bFGF) in primate models. J. Dent. Res 2001;80(12):2075–2079. KI-TAE KOO,CRISTIANO SUSIN, ULF M.E. WIKESJOÂ ¨, SEONG-HO CHOI, AND CHONG-KWAN KIMI. Transforming Growth Factor-b1 Accelerates Resorption of a Calcium Carbonate Biomaterial in Periodontal Defects. J Periodontol 2007;78:723-729. KARUPPANAN P. SASIKUMAR, SUGUMARI ELAVARASU, AND JAYAPRAKASH S. GADAGI. The application of bone morphogenetic proteins to periodontal and peri-implant tissue regeneration: A literature review. J Pharm Bioallied Sci. Aug 2012; 4(Suppl 2): S427–S430. SUBRAMANIAM M RAO, GAURI M UGALE, AND SHIVARAJ B WARAD. Bone Morphogenetic Proteins: Periodontal Regeneration. N Am J Med Sci. Mar 2013; 5(3): 161–168.

Free College Admissions Essays - MS Will Not Kill My Dream :: College Admissions Essays

MS Will Not Kill My Dream My story with MS began on December 4, 1999. I arrived at school as usual that cold winter morning feeling pretty good, a little tired, but other wise ok. Upon parking my car and opening the door to get out my right arm went to "sleep." I was totally blown away by it. How bizarre I thought to myself and just sat there a moment trying to figure out what possibly could be wrong with my arm. The next two days brought no relief and if anything it seemed to be getting more intense. My WHOLE arm was asleep and I just couldn't understand it. I visited a chiropractor a couple of days later and she said I was dehyrdrated and that my nervous system was under attack. Little did I know! I became increasingly concerned as the days passed and just couldn't buy what everyone was telling me, that I had a pinched nerve. I just knew it was something more and it was! I found a doctor about two weeks later and by that time my right hand was barely useable and the right side of my face, head and chest had also gone numb. I was scared to death! This doctor was wonderful and immediatly ran tests, sent me to a specialist, (neurologist) and spent hours with me examining me and trying to figure out just what could be wrong with me! MS never crossed my mind. A nurse of over ten years I have taken care of only ONE MS patient, a lady in her 90's! MS just didnt occur to me. After several visits to the neurologist, MRI, spinal tap and a slew of blood work I was told that MS was VERY likely the culprit. I was, to say the least, devastated by this news. I cried and cried and greived over this. It was with great fortune that a lady I worked with became extremly helpful to me during this time and prayed for me, listened to me and on more than one occasion, let me cry on her shoulder. On March 4, 2000 I visited a MS specialist at Dartmouth Hitchcock Hospital in Lebanon N.H. and he made it official that it was MS and immediatly started me on Avonex. At this point I had researched the disease endlessly, somewhat come to terms with this awful fate and began to think more positively.

On Pathography

Why do humans write them? Robert Maunder, a physicists and professor, illustrates an essay called, â€Å"On Photography,† that presents meta-commentary stories In Body & Soul. The genre of literature called, â€Å"photography,† describes his essay and Interest about being sick. Maunder establishes terms such as battle, triumph and survivor to reflect on the narratives of Illness. He describes his essay through elements of critical thinking by clarity, evidence of support and assumptions underlying the argument. As a result, Robert Maunder clearly manifest his main proposal successfully.Maunder expresses the clarity of his main argument of photography through his beliefs. For several of patients, to triumph over sickness, signifies an important part of the experience. The best photographers, in Maunders eyes, are those â€Å"like the best novels and poems, {he} suppose, describe life with subtlety contradiction, emotion, depth, beauty and banality. But it helps to read the best† (Maunder, 2004). Sometimes, the most efficient teaching lad Is to analyze and read written accounts of one's aspect from sickness or facing death as It can receive empathy towards one another.Patients who are diagnosed with a terminal Illness can evoke fear, depression and anger. However, Maunder also believes that the best photographers are those â€Å"who are curious and unashamed enough to write about what illness has done to their minds and preferences and relationships† (Maunder, 2004). It indicates that the existential truth is a familiar Indus of reflection for a sick writer, which the author compares to personal victory. The capability of understanding and connecting tit one and another is faint. Maunder argues how â€Å"a critically ill person needs above all is to be understood.Dying is a misunderstanding that you have to get straightened out before you go† (Maunder, 2004). Sickness cannot be acknowledged for understanding, until your friends and family, with love, recognize the absolute knowledge of your chronic disease. Thus, the clarity of his main argument Is pushed by his beliefs. He contributes his mall argument through personal observations, reflection, and anecdotes, as he not only try to convince the reader, but also himself. Maunder uses personal observation with his patients and students by reading photographers of other authors.He begins with Robert Mason Lee's photography, of his pain of Chronic disease, where his audience was conveyed by â€Å"the experience of that particular pain very well to someone who has never felt it. † (Maunder, 2004). He explains how a powerful writer has the unique ability to express their connections to feelings and awaken our senses. These senses are within others and us, where it results to think in synthesizing ways. Maunder also uses personal, short and amusing vents to account his message across.For example, he has read â€Å"few other essays where the author Is so c ompletely alive and present In the text, in all his narcissistic, gleeful, annoying, contemplative splendor,† such as Anatoly Broad (Maunder, 2004). Board's wrote a photography called, â€Å"Intoxicated by My Illness,† as he was dying of prostate cancer. This photography captivated Maunder eye's due to his bright and insightful personality, where did not take sickness as a serious event, but by convinced that â€Å"illness is a test of relationship, of values, and of faith-but as Job caches us, it is a test that, once passed, continues nonetheless† (Maunder, 2004).Illness and life are similar. However, illness can render as the greatest destroyer of denial where it has the power to reach a person's soul negatively. These personal experiences assist Maunders main argument. Maunder also apply his assumptions to propel his argument forward. He postulates how humans view their morality is recognized. He believes how â€Å"the battle metaphor of destruction is not ap propriate in this instance either. What serious illness does to denial is make it obvious† (Maunder, 004).Young children, teenagers and adults, are almost always solipsistic, that it affects their worldview. A sickness is Just to overcome, whereas older people, it becomes more of a challenge because they dwell on it, which can consume them. As a result, it changes their mindsets for the worst. Maunder continues his assumptions for how the society views on morality by providing the idea that one can truly live when they are faced with a death crisis. He brings â€Å"another version of the hope for redemption through illness† (Maunder, 2004).Maunder imagines his hopes for others who have suffered through illnesses, where it might illuminate certain situations and help gain perspective. For a while, Maunder takes a step back from writing illness narratives and explores into the genre of literature, consisting of stories regarding the aspects of sick patients. He argues tha t â€Å"triumphant battles, how much they actually do convey an important part of the experience of being sick for many people,† is an expectation (Maunder, 2004). Humans, who struggle with chronic illness(s), are the toughest of the tough.They are able to continually face the struggles of life and battle a debilitating disease than those who appear to live with it. Consequently, Maunder takes granted for people who lack of the knowledge of being sick to drive his topic ahead. In summary, Robert Maunder proves his main idea thoroughly and distinctly. He uses clarity, evidence for support and assumptions to underlie the principle of the argument. Maunder narrates photographers about being sick and communicates an extraordinary manner to an incomprehensible audience who Just needs to understand.

Japanese Female Apparel Market For Japanese Women Essay

While the bubbly outfits with overflowing laces and floral patterns that highlight the soft and sensitive characteristics once dominated the female apparel market in Japan, nowadays, Japanese women prefer balancing out the femininity with some stylish mannish clothing. Figure 3, where the woman matched her black lace dress and high heels with an olive-green military jacket, perfectly exemplifies the chic â€Å"甘è ¾â€ºÃ£Æ'ŸãÆ'Æ'ã‚ ¯Ã£â€š ¹Ã£â€š ³Ã£Æ' ¼Ã£Æ'‡â€  (The sweet-and-sexy coordinates) adored by many Japanese female consumers. The concept of â€Å"甘è ¾â€ºÃ£Æ'ŸãÆ'Æ'ã‚ ¯Ã£â€š ¹Ã¢â‚¬  is so well received in Japan because it spices up the overall look with an exquisite aesthetic balance. Known for wanting to break away from the mainstream, young Japanese female quickly adopted MA-1 jacket and the â€Å"girly-military look† as a mean to expressive their individualism in contradiction to social norms. As a result, MA-1 jacket has slowly become a wardrobe staple for Japanese young women. Another significant aspect of MA-1 jacket that helps it secure its top-ranked position is its ability to â€Å"casual down† a dressy outfit. Directly translated from the Japanese-made English word, ã‚ «Ã£â€š ¸Ã£Æ' ¥Ã£â€š ¢Ã£Æ' «Ã£Æ'€ã‚ ¦Ã£Æ' ³, â€Å"casualing-down† coordinates means to dress-down, or to break down the formality of fancy clothing (FASHION PRESS). A notable change in style has swept over Japan when people began to embrace apparels that value both comfort and personal style. According to a survey conducted by Jiratanatiteenun, Mizutani, Sato, Kitaguchi, and Kajiwara in 2011, â€Å"Casual [style] was theShow MoreRelatedUniqlo Assessment Presentation and Project Report Environmental Analysis Apparel Brand Management1066 Words   |  5 PagesIntroduction UNIQLO was a Japanese apparel brand under UNIQLO Co., Ltd established in 1974. They offered â€Å"MADE FOR ALL† high quality causal wear at competitive price. The firm had earned a huge success and high reputation. 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Executive Summary†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.†¦3 2. Environmental Analysis†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.†¦.3 2.1 Apparel Market Analysis†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.†¦.3 2.2 Competitive Analysis†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢ € ¦.†¦5 2.3 SWOT Analysis†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.7 3. Objectives†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦10 4. Marketing Strategies†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦12 5. Detailed Action Plan†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦ †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Read MoreStanding Tall: Japan’s Resilient Luxury Market5129 Words   |  21 PagesResilient Luxury Market Brian Salsberg Naomi Yamakawa Photograph: Abbie Chessler 2 In the immediate aftermath of the tsunami, earthquake and nuclear disaster that hit Japan last year, killing 19,000 people and battering the nation’s already shaky confidence, it was hardly surprising that people didn’t feel like shopping. At the time, the conventional wisdom was that such restraint was likely to last. People would still have to shop for essentials, of course, but the market for things like